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在接受耐用左心室辅助器件的患者中,针对主要设备相关感染的换

Sophie R Persaud¹, Michael Pienta², Donald S Likosky²

¹Department of Biomedical Engineering, University of Michigan Rackham Graduate School, Ann Arbor, Michigan.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

|December 6, 2024

概括

在长期左心室辅助器件 (dLVAD) 植入后,用于与设备相关的感染 (DRI) 的换 (PE) 在大多数患者中取得成功. 在4个月内进行早期干预可以改善结果并降低随后的DRI风险.

科学领域:

心脏病学心脏病学
医疗器械医疗器械
传染性疾病传染性疾病

背景情况:

与设备相关的感染 (DRI) 是永久左心室辅助器件 (dLVAD) 植入后的重大并发症,导致发病率和死亡率.
对DRI进行换 (PE) 后评估结果对于管理dLVAD患者至关重要.

研究的目的:

评估耐用左心室辅助装置 (dLVAD) 植入后患有设备相关感染 (DRI) 的患者的换 (PE) 结果.
为了确定成功率,存活率和随后的DRI的发病率,在PE后对DRI进行PE.

主要方法:

在2007年1月至2022年12月期间为主要DRI进行PE的49名患者的回顾性审查.
分析的结果包括生存率,随后的DRI发病率和PE后1年的DRI自由.

主要成果:

患者的中位数年龄为49岁,从初级植入到DRI诊断的中位数为26个月.
从DRI诊断到PE的中位时间为4.1个月. 76%的患者取得了成功 (在1年内摆脱DRI).
早期PE的成功率较高 (诊断后≤4个月:96%) 与晚期PE (>4个月:56%) 相比.

结论:

在dLVAD患者的设备相关感染管理中,换通常是成功的.
然而,随后的DRI和死亡风险仍然很大.
在DRI诊断后4个月内进行PE显著提高了成功率,并降低了复发感染的风险.

关键词:

心脏衰竭是因为心脏衰竭.左心室辅助装置的使用与设备相关的重大感染.机械循环支持机械循环支持交换交换交换的时间

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