化PAH和替代型氨酸的发育毒性:结构细微差别导致多种毒性和AHR激活

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Updated: Jun 5, 2025

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
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High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC

Published on: May 10, 2016

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Mackenzie L Morshead1, Lisa Truong1, Michael T Simonich1

  • 1Department of Environmental and Molecular Toxicology and the Oregon State University Superfund Center, Oregon State University, ALS 1007, Corvallis, OR, 97331, USA.

Chemosphere
|December 6, 2024
PubMed
概括

这项研究选了斑马鱼中的104种基化多环芳 (PAH),发现替代类型和位置显著影响PAH毒性和基碳水化合物受体 (AHR) 激活. Cyp1a诱导并不总是毒性的可靠指标.

关键词:
基化基化基化阿里碳水化合物受体是什么?这是一个Cyp1a类型.细胞染色体P450的使用.南烯 (Phenanthrene) 是一种存在于体内的物质.多环芳香碳化合物 多环芳香碳化合物

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