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Updated: Jun 5, 2025

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SSBP1积极调节RRM2,影响人类肺腺癌细胞的表皮介质转变和细胞循环停止

Xingyu Yang1, Bingfeng Ma1, Yafeng Liu1

  • 1Department of Immunology, School of Medicine, Anhui University of Science and Technology, Huainan City, China; Anhui Province Engineering Laboratory of Occupational Health and Safety, School of Medicine, Anhui University of Science and Technology, Huainan City, China.

Cellular signalling
|December 6, 2024
PubMed
概括

高SSBP1表达与肺腺癌 (LUAD) 的预后不佳相关. SSBP1通过上调RRM2来促进LUAD进展,这表明SSBP1/RRM2是潜在的治疗点.

关键词:
细胞循环的细胞周期皮质 - 介质细胞过渡 (EMT)氨酸介导的运动受体 (HMMR)肺腺癌 (LUAD) 是一种肺腺癌.核糖酸减少酶M2 (RRM2) 的作用.单链DNA结合蛋白1 (SSBP1) 是一种单链DNA结合蛋白.

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