通过对临床药房服务的元分析,评估系统审查的方法质量:AMSTAR-2的灵敏度分析
Inajara Rotta1, Joyce A Diniz2, Fernando Fernandez-Llimos3
1Department of Pharmacy, Federal University of Paraná, Curitiba, Brazil.
Research in social & administrative pharmacy : RSAP
|December 6, 2024
概括
大多数对临床药房服务进行元分析的系统审查质量极低. 修改对多次系统审查的评估2 (AMSTAR-2) 工具
科学领域:
- 药房实践 在药房实践中
- 基于证据的医疗保健
- 研究方法研究方法研究方法学
背景情况:
- 系统性审查与元分析 (SRMA) 对于基于证据的医疗保健决策至关重要.
- 专项管理机构的有效性取决于其行为和报告质量.
- AMSTAR-2是评估SRMA质量的关键工具,有七个关键领域.
研究的目的:
- 为了评估SRMA的质量,专注于临床药房服务.
- 为了确定改变AMSTAR-2域的关键性对质量评估的影响.
主要方法:
- 在PubMed,Scopus和Web of Science进行了系统的搜索,更新至2023年1月1日.
- 包括对已识别的SRMA的手动参考列表搜索.
- 使用AMSTAR-2评估SRMA方法质量,通过假设删除关键域名称来分析变化.
主要成果:
- 在153个符合条件的SRMA中,90.2%的质量极低,8.5%的质量低,1.3%的质量中等.
- 假设删除AMSTAR-2的关键域名称并没有显著改变整体质量评估.
- 所有关键的AMSTAR-2领域在药房实践研究中都被认为是必不可少的.
结论:
- 大多数临床药房服务的SRMA都表现出极低或低的方法质量.
- 调整AMSTAR-2域的关键性并没有提高质量评估结果.
- 提高SRMA质量对于强有力的制药服务证据至关重要,需要研究人员,编辑和审稿人的协作努力.
相关概念视频
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
120
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
120
01:16Clinical Trials
6.6K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.6K
01:20Comparing the Survival Analysis of Two or More Groups
150
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
150
01:14SBAR II: Application of SBAR
4.3K
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
4.3K
01:15Data Validation
142
Method validation is a crucial process in analytical chemistry designed to confirm that a given method consistently produces reliable and high-quality results. This process is essential when a method is applied to different sample matrices or when procedural modifications are made, ensuring that the results meet acceptable standards across various applications.
Key parameters for method validation include:
Key parameters for method validation include:
142