孤独,社会孤立的性别差异及其对精神病症状和精神分裂症认知功能的影响
Jinghui Chi1, Nannan Liu2,3, Tian Tian1
1Department of Psychiatry, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, No. 13, Liulin Road, Hexi District, Tianjin, 300222, China.
BMC psychiatry
|December 6, 2024
概括
男性精神分裂症患者经历更多的孤独和社会隔离,这与精神病症状相关. 女性患者的女性患者.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 社会心理学 社会心理学
背景情况:
- 与一般人群相比,精神分裂症 (SCZ) 患者的社会隔离和孤独率更高.
- 这些功能失调的社会关系是SCZ患者护理中的重要问题.
- 探索这些经验中的性别差异对于有针对性的干预至关重要.
研究的目的:
- 研究中国慢性精神分裂症患者中孤独和社会隔离的性别差异.
- 检查孤独,社会隔离,精神病症状和SCZ男性和女性患者的认知功能之间的关系.
主要方法:
- 评估了323名SCZ患者 (136名男性,187名女性).
- 评估心理病理学 (PANSS),认知功能 (RBANS),孤独 (UCLA孤独量表) 和社会隔离 (ISI).
- 多种线性回归模型分析了孤独和社会隔离对结果的影响,按性别分层.
主要成果:
- 男性SCZ患者报告的孤独感和社会隔离感明显高于女性.
- 在男性中,孤独和社会隔离都预测了精神病症状严重程度的增加 (PANSS分数).
- 在女性中,孤独与认知功能负相关,包括即时记忆,语言,延迟记忆和整体认知表现 (RBANS分数).
结论:
- 孤独和社会孤立在男性SCZ患者中更为普遍.
- 在男性SCZ患者中,这些因素与更大的精神病症状负担有关.
- 在女性SCZ患者中,孤独与较差的认知功能有关.
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