透明对齐剂与传统支架对氧化剂和抗氧化剂水平的影响:一项案例对照研究
Betul Yuzbasioglu Ertugrul1, Ilknur Veli2, Abdullah Seckin Ertugrul3
1Department of Orthodontics, Dokuz Eylul University Faculty of Dentistry, Izmir, Turkey.
概括
与传统支架 (CB) 相比,清晰支架 (CA) 可能会减少在正牙治疗期间的氧化组织损伤. 在牙沟液中,CA显示了较低的总氧化剂状态 (TOS) 水平,这表明氧化应激较少.
科学领域:
- 生物医学工程 生物医学工程
- 牙周病学 牙周病学
- 矯正牙科 矯正牙科是一種矯正牙科.
背景情况:
- ортодонтика治疗涉及机械力量,可以诱导氧化应激.
- 牙裂液 (GCF) 反映了本地组织对治疗的反应.
- 将常规支架 (CB) 和清晰对齐器 (CA) 之间的氧化应激标记进行比较至关重要.
研究的目的:
- 评估GCF在正牙治疗期间总氧化剂状态 (TOS) 和总抗氧化剂状态 (TAS) 的变化.
- 为了比较30天内接受CBs和CAs治疗的患者之间的氧化应激水平.
主要方法:
- 在基线,第7天和第30天从34名患者 (CBs vs. CAs) 收集的GCF样本.
- ELISA用于测量GCF中的TOS和TAS水平.
- 评估用于评估组织健康的临床牙周指标.
主要成果:
- 清晰对齐 (CA) 组在第7天呈现过渡性高TOS,到第30天恢复到基线.
- 常规支架 (CB) 组在第7天和第30天表现出持续高的TOS.
- 两组都没有观察到TAS的显著变化;CA组的TOS较低,牙周指数比CB组更好.
结论:
- 清晰对齐器治疗可能会导致在正义牙牙移动期间氧化组织损伤较少.
- 在高氧化应激令人担忧的情况下,CA治疗可能是更好.
- 需要进一步研究氧化应激在正牙治疗中的长期影响.
相关概念视频
01:20Radical Autoxidation
2.1K
The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
2.1K
01:25Strategies for Assessing and Addressing Confounding
83
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
83
01:17Oxidation of Phenols to Quinones
2.9K
In the presence of oxidizing agents, phenols are oxidized to quinones. Quinones can be easily reduced back to phenols using mild reducing agents. The electron-donating hydroxyl group enhances the reactivity of the aromatic ring, enabling oxidation of the ring even in the absence of an α hydrogen.
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
2.9K