尼日利亚和加纳的酒精消费与中风之间的关联:一个病例控制研究
Innocent Ijezie Chukwuonye1, Onoja Matthew Akpa2, Osahon Jeffery Asowata2
1Department of Medicine, Federal Medical Centre Umuahia, Umuahia, Nigeria.
概括
目前的酒精消费与尼日利亚和加纳中风风险更高有关. 沉重,狂饮和适度饮酒显著增加中风风险,而以前的饮酒显示没有关联.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 酒精消费是一个全球性的健康问题,区域模式各不相同.
- 了解不同人群中与酒精相关的特定风险对于有针对性的干预至关重要.
研究的目的:
- 调查饮酒模式与中风发病率之间的关联.
- 在尼日利亚和加纳成年人中区分与不同水平的酒精摄入量相关的中风风险.
主要方法:
- 一个多中心的病例控制研究,涉及7368名参与者 (中风病例和年龄/性别匹配的对照).
- 酒精消费是自我报告的,并分为禁酒者,前饮酒者和目前饮酒者 (根据饮酒水平进一步分类).
- 使用条件后勤回归模型,逐渐调整人口,生活方式,饮食和代谢因素.
主要成果:
- 在最初的模型中,当前饮酒者与中风有显著的关联 (几率比:1.19-1.17).
- 适度,重度和暴饮暴饮的饮酒水平显示出与中风的持续,显著的关联.
- 在完全调整的模型中,轻度酒精消费与中风没有显著的关联.
结论:
- 目前的酒精消费,特别是中度,重度和狂饮水平,与中风风险增加有显著的关联.
- 这些发现强调了解决有害饮酒模式在西非中风预防方面的重要性.
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