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Updated: Jun 5, 2025

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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哺乳动物基因表达的细胞特异控制使用DNA修复可诱导的 ribozyme 开关

Jieling Hong1, Zhen Jiang1, Zhenkun Wu1

  • 1State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Biomedical Sciences, Hunan University, Changsha, 410082, China.

Angewandte Chemie (International ed. in English)
|December 7, 2024
PubMed
概括

研究人员创建了一个DNA修复激活的 ribozyme 开关,用于精确的基因表达控制. 该系统针对癌细胞,并使体内基因编辑成为可能,抑制瘤生长,用于先进的基因治疗.

关键词:
化学修饰的等离子体测量DNA修复的时间.功能性核酸是一种功能性核酸.基因表达调节 基因表达调节基因治疗是一种基因疗法.

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