复杂的轨迹与患有先天性胃肠道形的2岁婴儿的神经损伤有关
Manon Midavaine1, Nicolas Vinit2, Victor Sartorius1,3
1Department of Neonatology, Necker-Enfants Malades University Hospital, APHP, Paris, France.
Acta paediatrica (Oslo, Norway : 1992)
|December 7, 2024
概括
在患有先天性胃肠道形的婴儿中,有9%的婴儿在两岁时经历发育迟缓. 长时间的新生儿重症监护和住院增加了这种风险,而母乳养可能会提供保护.
科学领域:
- 儿科手术 儿科手术
- 新生儿科学 新生儿科学
- 发育儿科 发育儿科
背景情况:
- 先天性胃肠道形需要手术干预,并可能影响婴儿的发育.
- 这一群人的神经发育结果需要进一步研究.
研究的目的:
- 描述两岁时患有先天性胃肠道形的婴儿的神经发育状况.
- 在这个队列中确定与发育迟缓相关的因素.
主要方法:
- 对118名因胃肠道形而接受手术的婴儿进行了回顾性队列研究.
- 用年龄和阶段问卷 (ASQ) 评估24个月的神经发育.
- 发育迟缓被定义为总ASQ得分≤185.5.
主要成果:
- 9% (11/118) 的婴儿表现出发育迟缓 (ASQ ≤185).
- 与延迟相关的因素包括更早的妊娠年龄,更长的侵入性通风和长时间的亲肠营养.
- 住院病例的增加和新生儿重症监护室 (NICU) 停留时间的延长与发育迟缓有显著联系.
结论:
- 显著比例的患有胃肠道形的婴儿在两岁时出现发育迟缓.
- 长时间的NICU住院和多次住院是神经发育障碍的危险因素.
- 哺乳可能会对神经发育结果产生保护作用.
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