在CRISPR-Cas9查中,基于必要的癌症基因,发现了新的皮肤黑色素瘤亚型

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Updated: Jul 11, 2026

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity
07:52

In Vivo CRISPR/Cas9 Screening to Simultaneously Evaluate Gene Function in Mouse Skin and Oral Cavity

Published on: November 2, 2020

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Yi-Xiao Wang1,2,3,4, Zhang-Jun Ding5,6, Qian-Ling Wang7

  • 1Department of Dermatology, The First Affiliated Hospital, Anhui Medical University, Hefei, 230032, Anhui Province, China.

Archives of dermatological research
|December 7, 2024
PubMed
概括

这项研究确定了皮肤黑色素瘤 (CM) 亚型的关键基因,揭示了分子,免疫和风险亚型与患者的预后和免疫治疗反应相关. 在黑色素瘤中,RABIF被验证为潜在的治疗标.

关键词:
克里斯普尔-Cas9是什么意思临床管理 临床管理皮肤黑色素瘤是一种皮肤黑色素瘤.重要的癌症基因免疫组织化学 免疫组织化学分子子类型 分子子类型预测模型是一个预测模型.拉比夫 (Rabif) 是一个关税制国家.风险子类型 风险子类型组织微型阵列.

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