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Updated: Aug 9, 2026

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow
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Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

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开发一种LC-MS/MS方法,用于同时量化小鼠血中的11种 perfluoroalkyl化合物,用于毒动力学应用

Chloé Ml Argoul1, Yannick Dauwe2, Laïla Lakhal2

  • 1INTHERES, Université de Toulouse, INRAE, ENVT, Toulouse, France; ToxAlim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France.

Journal of pharmaceutical and biomedical analysis
|December 7, 2024
PubMed
概括

一种新的分析方法允许在小鼠血中同时测量11种per-和多基物质 (PFAS). 该方法支持对新兴PFAS替代品的毒动力学 (TK) 研究,解决其安全性概况中的数据缺口.

关键词:
液体色谱学 液体色谱学 液体色谱学质谱测量质量谱测量perfluoroalkyl 物质是一种高醇基物质.有毒动力学有毒动力学

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相关概念视频

High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...