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Updated: Jun 5, 2025

Improved Polymerase Chain Reaction-restriction Fragment Length Polymorphism Genotyping of Toxic Pufferfish by Liquid Chromatography/Mass Spectrometry
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对离子配对逆相液态色谱的评估,用于分离大型RNA分子

Jonathan Maurer1, Camille Malburet2, Marc François-Heude2

  • 1Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel Servet 1, 1211, Geneva, Switzerland; School of Pharmaceutical Sciences, University of Geneva, Geneva, Switzerland; mRNA Center of Excellence, Analytical Sciences, Sanofi, 1541 Avenue Marcel Mérieux, 69280 Marcy l'Etoile, France.

Journal of chromatography. A
|December 7, 2024
PubMed
概括

这项研究优化了离子配对逆相液态色谱 (IP-RPLC) 用于大RNA的表征. 适度疏水的离子配对剂 (IPAs) 和特定条件显著改善了用于治疗的RNA分离和完整性分析.

关键词:
基胺是一种基胺.离子配对逆相液态染色学产能峰值时间是产能峰值时间.这是一个RNARNARNARNARNA.选择性的选择性

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