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母胎肥胖对母乳成分和母乳养结果的早期产后影响

Carolina Dumke de Siqueira¹, Leandro Borges², Tamara Dal Mora¹

¹Post-Graduation Program in Pharmacy, Health Sciences Centre, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

Clinical nutrition ESPEN

|December 7, 2024

概括

母亲的炎症和超重状态可能会影响母乳养的开始和新生儿的体重. 然而,母乳的成分保持稳定,尽管有炎症标志物,但仍能为婴儿提供必要的营养.

科学领域:

产科和妇科产科和妇科
新生儿科学新生儿科学
免疫学免疫学免疫学

背景情况:

由于慢性轻度炎症,对于超重或肥胖的母亲来说,母乳养往往是一项挑战.
妊娠前的体重指数会对乳糖生成II产生负面影响,即乳母分泌的开始.
孕产妇的炎症和代谢状态会影响新生儿的结果.

研究的目的:

为了评估产后母亲的炎症,代谢状况和母乳成分.
将这些因素与母亲的营养和母乳养状况联系起来.
了解母亲体重和炎症对母乳养和婴儿健康的影响.

主要方法:

产后24小时和48小时,对来自母亲的血清和母乳样本进行分析.
测量炎症生物标志物 (例如SAA,CRP,TNF-α),生殖激素和母乳成分 (蛋白质,脂肪酸,卡路里).
六个月的随访,以评估母乳养的结果.

主要成果:

与抗炎性IL-10相比,母乳中发现有较高的促炎生物标志物 (SAA,CRP,TNF-α,IL-8,IFN-γ) 度.
怀孕后超重的母亲的新生儿出生时体重高于怀孕后体重健康的新生儿.
在不同母亲的营养状况和出生类型中,母乳成分保持稳定.

结论:

孕产妇超重/肥胖相关的炎症可能会挑战乳糖生成II并影响新生儿出生体重.
母乳表现出稳定的成分,可靠地滋养婴儿,无论母亲的因素.
在母乳中存在的促炎生物标志物需要进一步调查婴儿健康影响.

关键词:

母乳的成分母乳的成分哺乳期哺乳期哺乳期哺乳期哺乳期是一个孕产妇营养孕产妇的营养

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