使用磁盘信号强度指数对宫椎盘退化的定量评估
Koki Tsuchiya1, Ichiro Okano2, Ali E Guven3
1Spine Care Institute, Hospital for Special Surgery, New York, NY, USA; Department of Orthopaedic Surgery, Showa University School of Medicine, Tokyo, Japan.
概括
盘信号强度指数 (DSI2) 量化了宫盘退化,将年龄,BMI和糖尿病确定为关键风险因素. 这种方法为未来的研究提供了对主观评分系统的有希望的替代方案.
科学领域:
- 放射学和成像学 放射学和成像学
- 脊柱外科手术 脊柱外科手术
- 退行性磁盘疾病研究研究
背景情况:
- 评估宫椎间盘退化缺乏一个黄金标准,不像腰椎分级.
- 磁盘信号强度指数 (DSI2) 之前被开发用于腰椎盘的评估.
- DSI2在椎中很容易测量,提供了定量方法.
研究的目的:
- 将DSI2方法应用于椎椎间盘.
- 通过使用DSI2.2,调查与宫椎盘退化相关的因素.
- 建立DSI2作为宫椎盘评估的可靠工具.
主要方法:
- 从接受ACDF (2015-2018) 患者的宫MRI的回顾性分析.
- 在使用脑脊液 (CSF) 作为参考的中腰部T2加权图像上进行的DSI2测量.
- 多变量线性回归模型分析了人口统计和并发症数据与DSI2得分的比较.
主要成果:
- DSI2分数与Pfirrmann等级的反向相关,表明退化.
- 年龄,BMI和Modic变化 (1型) 独立地与增加的磁盘退化有关.
- 糖尿病病史显示与较高的DSI2得分相关,而C4/5和C7/T1段较不容易变性.
结论:
- DSI2是识别子宫退行性疾病的危险因素的宝贵工具.
- DSI2方法显示出作为主观评分系统的客观替代方案的希望.
- DSI2在检测宫脊椎中微妙的磁盘退化进展方面表现出色.
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