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相关概念视频

What is Monogastric Digestion?01:50

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The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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Bacterial Flora of the Large Intestine01:29

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The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
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相关实验视频

Updated: Jun 5, 2025

Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
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胃肠道恶性瘤中的微生物群

Ludovica Bricca1, Serena Porcari2, Edoardo Savarino1

  • 1Department of Surgical Oncological and Gastroenterological Science (DiSCOG), Gastroenterology Unit, University of Padova, Padova, Italy.

Best practice & research. Clinical gastroenterology
|December 7, 2024
PubMed
概括

这篇评论考察了肠道微生物群.

关键词:
胃肠道的恶性瘤.胃肠道癌前期的癌症.微生物群中的微生物群.

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科学领域:

  • 胃肠道瘤学 胃肠道瘤学
  • 微生物组研究 微生物组研究
  • 癌症流行病学 癌症流行病学

背景情况:

  • 人的肠道是一个复杂的微生物生态系统.
  • 微生物群组成的变化与各种疾病有关,包括癌症.
  • 了解微生物群在癌前病变中的作用对于早期检测和预防至关重要.

研究的目的:

  • 提供与癌前病变相关的微生物群概况的概述.
  • 批判性地审查现有关于微生物群和瘤疾病之间的联系的数据.
  • 确定当前微生物群分析方法的挑战和变异性.

主要方法:

  • 关于微生物群和癌前病变研究的综合文献综述.
  • 对用于微生物群概况的方法进行批判性分析.
  • 综合不同解剖部位 (食道,胃,大肠) 的发现.

主要成果:

  • 微生物群分析方法存在显著的变异性,可能会影响结果.
  • 在特定的微生物群落和癌前病变之间观察到一致的联系.
  • 微生物群的变化涉及到各种情况下的瘤遗传级联.

结论:

  • 微生物群在胃肠道癌前病变的发展中起着重要作用.
  • 对于可靠的关联研究,微生物群分析方法的标准化是必要的.
  • 进一步的研究可以阐明微生物群在癌症预防和早期诊断中的作用.