在接受透析治疗的患者中血栓形成的发生率:系统性审查和元分析
Parisa Shiri1, Shabab Rezaeian2, Alireza Abdi3
1Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
概括
血栓形成会影响14.2%的透析患者,特别是那些有血管通道的患者,如动脉静脉移植. 建议对血液透析患者采取预防措施,包括抗凝剂,以减轻风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 血管外科 血管外科
- 流行病学 流行病学
背景情况:
- 血栓形成是透析患者血管接入功能障碍的主要原因.
- 现有的研究表明,患病率各不相同,需要进行全面分析.
- 这项研究解决了对透析人群中血栓形成患病率进行系统评估的需要.
研究的目的:
- 确定在接受透析的患者中血栓形成的总体患病率.
- 确定与较高的血栓形成率相关的人口和访问相关因素.
- 为透析患者预防血栓形成提供基于证据的建议.
主要方法:
- 系统审查和对2023年12月之前发表的研究进行元分析.
- 关键词包括"血栓形成"",末期病"",血液透析"和"透析".
- 用随机效应模型分析数据,以I2指数评估异质性,通过STROBE检查清单评估研究质量.
主要成果:
- 血栓形成的总体患病率为14.2% (95% CI:11.5-17.2).
- 在50岁以下的患者 (17.1%) 和血管接入,特别是动脉静脉移植 (22.8%) 的患者中观察到更高的患病率.
- 晚期血栓形成 (15.0%) 比早期血栓形成 (5.3%) 更为普遍.
结论:
- 血栓形成在透析患者中非常普遍,动脉静脉移植显示出显著的风险.
- 这些发现强调了实施预防策略的重要性.
- 建议包括在血液透析患者中使用抗凝血药物,以减少血栓发生率.
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