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作为TRPML1的激动剂,ML-SA5通过促进 lysosomal exocytosis来减轻引起的毒性

Hongjing Zhang1, Yifei Wang1, Ruiyun Wang1

  • 1Institute of Radiation Medicine, Shanghai Medical College, Fudan University, No. 2094, Xie-Tu Road, Shanghai 200032, PR China.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|December 8, 2024
PubMed
概括

一种新型药物ML-SA5通过激活TRPML1和TFEB通路,有效地从脏中清除,减少小鼠的脏损伤. 这为中毒提供了一个有前途的治疗方法.

关键词:
拆分公司的拆分.lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis lysosomal exocytosis 是一种发生在细胞体内发生的细胞体中发生的细胞体中发生的细胞体.在 ML-SA5 中,毒性 毒性 毒性在TRPML1中使用.是一种.

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