重金属的来源导向风险及其对自然生物膜中抗性基因的影响
Hansen Xu1, Dan Zhu2, Mei Zhong2
1Institute of International Rivers and Eco-Security, Yunnan University, Kunming 650500, China; Yunnan Key Laboratory of International Rivers and Transboundary Eco-Security, Kunming 650500, China; Leshan Meteorological Bureau, Sichuan Province, Leshan 614000, China.
Journal of hazardous materials
|December 8, 2024
概括
河流生物膜中的重金属丰富了金属和抗生素耐药性基因,构成生态和健康风险. 工业活动对这些风险有很大影响,这凸显了在环境评估中监测生物膜的必要性.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 生态毒理学 生态毒理学
背景情况:
- 来自土地使用的重金属 (HMs) 将金属耐药性基因 (MRG) 引入河流,通过共同选择可能增加抗生素耐药性基因 (ARG).
- 生物膜是HM和耐药性基因积累的潜在热点,但它们在HM丰富和抗体影响中的作用未得到充分研究.
研究的目的:
- 为了研究海河生物膜中的HM度和物理化学特性.
- 分析HM积累,抗体 (ARG和MRG) 和生态/健康风险之间的关联.
主要方法:
- 从海河收集并分析了生物膜样本.
- 在生物膜中量化了九个HM (As,Cd,Co,Cr,Cu,Ni,Pb,V,Zn).
- 利用16S rRNA和元基因组测序来评估抗体和相关性.
主要成果:
- 工业活动 (As, Cu, V) 带来了更高的风险;自然,农业和运输来源也为HM贡献了.
- 生物膜显示了ARG和MRG的显著同时发生,与HM风险指数相关.
- 生物膜 (As) 度与ARG和MRG的丰度和表达正相关;pH受HM物种化的影响.
结论:
- 生物膜作为HM和抗性基因的关键储存库,将土地利用活动与河流抗性基因变化联系起来.
- 生物膜中的HM积累,特别是As,直接影响ARG和MRG,影响生态和健康风险.
- 将生物膜监测整合到环境管理中,对于评估水质和缓解耐药性基因传播至关重要.
相关概念视频
01:29Biofilms
Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
00:57The Periodic Table and Organismal Elements
176.3K
Overview
176.3K
01:30Development of Antibiotic Resistance
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
01:36Types of Toxins
1.6K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.6K
00:57Antibiotic Selection
52.3K
Overview
52.3K
01:28Gene Regulation in Microbial Communities: Quorum Sensing
1
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
1