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Updated: Jun 5, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Published on: May 25, 2018

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针对基因组编辑的双pH响应的CRISPR/Cas9核糖蛋白异复合体

Xianjin Luo1, Janin Germer1, Tobias Burghardt1

  • 1Pharmaceutical Biotechnology, Department of Pharmacy, Ludwig-Maximilians-Universität Munich, Butenandtstrasse 5-13, 81377 Munich, Germany.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
|December 8, 2024
PubMed
概括

新的异种 (XP) 有效地提供CRISPR/Cas9基因编辑工具,增强细胞吸收和基因组编辑. 这些适应pH的载体对治疗诸如杜申肌肉发育不良等遗传疾病有前途.

关键词:
克里斯普尔 Cas9 案例Cas9/sgRNA 核糖蛋白是一种核糖蛋白.基因组编辑 基因组编辑同质导向维修是同质导向维修的一种方式.这是一种Lipo-xenopeptide.

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