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计算机洞察力识别非同义单核酸多态变异影响互白素-4的结构和功能

Pratima Roy1, Siddharth Sharma1, Manoj Baranwal1

  • 1Department of Biotechnology, Thapar Institute of Engineering & Technology, Patiala, India.

Proteomics. Clinical applications
|December 8, 2024
PubMed
概括

计算分析在IL-4基因中发现了六种非同义单核酸多态 (nsSNP). 这些nsSNP可能会影响IL-4功能,并且是炎症性疾病中遗传测试的潜在候选者.

关键词:
互白素-4的使用方法模拟分子动力学和蛋白质稳定性的模拟突变点的突变点是指蛋白质构成的结构.

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