已知的高血压和中风风险持续时间的关联:REGARDS研究
George Howard1, Paul Muntner2, Daniel T Lackland3
1Department of Biostatistics (G.H., S.E.J.), School of Public Health, University of Alabama at Birmingham.
Stroke
|December 9, 2024
概括
延迟高血压的出现可能会降低中风风险. 较长的高血压持续时间与增加的药物使用,更高的血压和更大的中风风险相关,即使在调整后.
科学领域:
- 心血管疾病研究研究
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 高血压管理是减少心血管疾病的关键.
- 关于延迟高血压发作的好处的数据有限.
研究的目的:
- 调查公认高血压持续时间与发生中风风险之间的关联.
- 评估高血压持续时间对缩血压和抗高血压药物的使用的影响.
主要方法:
- 来自REGARDS队列研究的数据分析,包括黑人和白人参与者.
- 基于高血压持续时间的参与者的分层:正常血压,≤5年,6-20年和21年以上.
- 评估基线缩血压,药物类别和发生中风事件,并对相关风险因素进行调整.
主要成果:
- 较长的高血压持续时间与抗高血压药物类别的使用增加有关.
- 随着高血压持续时间的增加,观察到更高的平均静缩血压.
- 与正常血压患者相比,高血压持续时间较长时,中风风险危险比率显著增加.
结论:
- 长时间的高血压持续时间与血压升高,药物需求增加和中风风险增加有关.
- 这些发现表明,延迟高血压的出现可能会减轻中风的整体负担.
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