在为良性和恶性病理而接受甲状腺切除术的患者中,缺血和缺甲状腺症的预测因素
Jino Johns Lalitha1, Natarajan Ramalingam1, Remya Rajan2
1Department of Head & Neck Surgery, Christian Medical College, Vellore, India.
Endocrine oncology (Bristol, England)
|December 9, 2024
概括
这项研究确定了全甲状腺切除术后缺甲状腺症和缺血的关键风险因素. 预先存在的甲状腺功能低下症,中央隔间部解剖和样本中的甲状腺腺预测甲状腺功能低下症,而女性性别也预测了低血症.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 神经外科 神经外科
背景情况:
- 全甲状腺切除术是一种常见的外科手术手术.
- 手术后的小甲状腺功能低下和低血是常见的并发症.
- 了解风险因素对于患者管理至关重要.
研究的目的:
- 在全甲状腺切除术后识别过渡性甲状腺功能低下症的独立风险因素.
- 为了确定完全甲状腺切除术后过渡性低血症的独立危险因素.
主要方法:
- 来自300名接受全甲状腺切除术的患者的临床数据的回顾性分析.
- 多变量逻辑回归分析以确定缺甲状腺症和低血症的预测因子.
主要成果:
- 过渡性甲状腺功能低下的发生率为26.7%;过渡性低血是12.3%.
- 在手术前的甲状腺功能低下症,中央隔间部剖析 (CCND) 和手术样本中的甲状腺腺预测了甲状腺功能低下症.
- 女性性别,标本中的副甲状腺,和CCND预测了低血症.
结论:
- 甲状腺切除术后缺甲状腺症和缺血的独立预测因子不同.
- 副甲状腺功能低下症可能成为随后低血症的预测因素.
相关概念视频
01:17Hormones and Bone Tissue
2.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
2.6K
01:21Skeleton and Calcium Homeostasis
4.4K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
4.4K
00:59The Parathyroid Glands
1.9K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
1.9K
00:51Synthesis and Functions of Calcitonin
1.6K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
1.6K
01:20Synthesis and Regulation of Thyroid Hormones
4.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.2K
01:18Functions of Thyroid Hormones
2.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.5K