影响COVID-19患者死亡率的因素 患有先前存在的慢性脏疾病的患者
Shyama Shyama1, Harsh Vardhan2, Vishnu Shankar Ojha1
1Department of General Medicine, All India Institute of Medical Sciences, Patna, Bihar, India.
Indian journal of nephrology
|December 9, 2024
概括
在慢性病 (CKD) 患者中,COVID-19显著增加了死亡风险. 男性性别,年龄较大,侵入性通风和高炎症标志物是这些脆弱个体死亡的关键风险因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- COVID-19对慢性病 (CKD) 患者构成严重威胁.
- 了解患有COVID-19的CKD患者的死亡风险因素对于有效管理至关重要.
- 以前存在的功能障碍增加了对严重病毒感染的脆弱性.
研究的目的:
- 调查COVID-19患者的死亡风险因素,这些患者先前患有慢性病 (CKD).
- 确定与这种患者队列中死亡率增加相关的人口,临床和实验室参数.
主要方法:
- 对150名实验室确诊的COVID-19和先前存在的CKD的成年患者的回顾性分析.
- 数据收集包括人口统计,临床参数和实验室值.
- 卡普兰-梅尔曲线,Log Rank测试和考克斯回归分析被用来评估生存率和确定风险因素.
主要成果:
- 男性性别,晚年和侵入性通风与更高的死亡率有关.
- 炎症标志物 (白细胞计数,LDH,CRP,D-二次体,IL-6) 的升高显著增加了死亡风险.
- 该研究确定了COVID-19患有CKD的患者致命结局的关键预测因素.
结论:
- 患有CKD的COVID-19患者面临死亡风险增加.
- 诸如男性性别,年龄较大,需要通风和炎症升高等因素预测结果不佳.
- 针对这些因素的量身定制的管理策略对于降低患有CKD的COVID-19患者的死亡率至关重要.
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