相关实验视频
Updated: Jun 5, 2025

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.8K
在社区药房检测到的药物治疗问题INR检查
Jeff Nagge1, Michelle Moussa2, Amleset Zerai3
1School of Pharmacy, University of Waterloo, Kitchener, Ontario.
概括
社区药剂师使用点诊所 (POC) INR测试在接受华法林治疗的患者中发现了非华法林药物治疗问题 (nwMTP). 这突显了药剂师在改善抗凝管理期间全面的患者护理方面的作用.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 药物管理 药物管理
背景情况:
- 华法林仍然是加拿大的常见抗凝剂,传统上通过实验室INR测试进行管理.
- 新斯科舍省的社区药房抗凝管理服务 (CPAMS) 使用社区药剂师进行护理点 (POC) INR测试和华法林管理.
- 这种模型为识别非华法林药物治疗问题 (nwMTPs) 提供了机会.
研究的目的:
- 评估药剂师在POC INR测试中在心房的患者中发现的nwmtp的速率和类型.
- 评估药剂师对这些已识别的nwmtp进行的干预措施.
主要方法:
- 在诺瓦斯科舍省40家社区药房进行了前性,多中心的观察性研究.
- 药剂师在常规POC INR访问期间使用Qualtrics洞察平台记录了nwtMTP和干预措施.
- 数据是在6个月的时间内收集的.
主要成果:
- 在6个月内,13家药房报告了43个nwmtp.
- 估计的nwMTP检测率为每100个POC INR测试中的1.26 (95% CI,0.69到2.32).
- 最常见的nwmtp类别是"指示",通常需要额外的治疗;药剂师通常建议药物调整或患者教育.
结论:
- 药剂师在华法林治疗期间检测和管理各种药物治疗问题方面发挥着潜在的重要作用.
- 与指示相关问题的高率表明,华法林治疗患者的治疗需求尚未得到满足.
- 在社区环境中由药剂师领导的POC INR测试可以通过识别和解决nwmtp来增强综合患者护理.
相关概念视频
Errors occurring during blood pressure monitoring
601
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Several factors...
601
Drug Therapy
39
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
39
Pharmacovigilance
773
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
773
Renal Failure: Dose Adjustments
63
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
63
Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
41
Circadian rhythms are cyclic changes that are crucial in plasma drug concentrations. Various standard circadian parameters, including core body temperature, heart rate, and other cardiovascular factors, directly impact disease states and the therapeutic response to drug therapy.
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
41
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
1.2K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.2K

