内动脉瘤与垂体腺瘤共存:一个系统性审查
Mateus Gonçalves de Sena Barbosa1, Vinícius Otávio da Silva1, Luiz Henrique Santos Ferreira2
1Department of Neurosurgery, Atenas University Center, Passos, MG, Brazil.
Annals of medicine and surgery (2012)
|December 9, 2024
概括
内动脉瘤 (IA) 经常与大脑瘤 (BT) 一起存在,特别是垂体腺瘤 (PA). 对于这两种情况,手术干预是常见的,但需要仔细规划才能获得最佳的患者结果.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 神经外科 神经外科
背景情况:
- 内动脉瘤 (IA) 和原发性脑瘤 (BT) 经常一起发生, pituitary adenomas (PA) 是最常见的相关瘤类型.
- 据估计,这种共存发生在0.5-7.4%的病例中,突出显示了显著的临床重叠.
研究的目的:
- 审查关于内动脉瘤和垂体腺瘤同时发生的文献.
- 分析患者的人口统计,瘤特征,动脉瘤细节,治疗策略和结果.
主要方法:
- 使用主要数据库 (Medline,Embase,Scopus,Cochrane Library,Web of Science) 对1960年至2023年12月期间发表的文章进行了系统的文献审查.
- 数据提取的重点是动脉瘤和瘤特征,破裂状态,治疗建议,治疗顺序和患者的治疗结果.
主要成果:
- 该研究分析了来自25篇文章的118名患者,其中非功能性 (NFA) 和生长激素 (GH) 分泌腺瘤是最常见的.
- 手术是主要的治疗方法,采用各种切除技术. 很大一部分患者 (16.0%) 患有多重动脉瘤.
- 治疗时间有所不同,一些患者在PA手术前接受IA治疗 (21.2%) 和其他人接受同时治疗 (12.7%).
结论:
- 垂体腺瘤与内动脉瘤的显著流行有关,这可能是由于荷尔蒙失衡和机械影响.
- 手术管理需要仔细考虑,以防止并发症.
- 进一步的纵向研究和详细的随访对建立最佳治疗指南至关重要.
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