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Updated: Jun 5, 2025

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DENND5B 基因表达作为糖尿病-外周动脉疾病发展的触发因素:来自单变和多变孟德尔随机化研究的见解

Qiaoqiao Li1, Fuli Cao2, Xueping Gao3

  • 1Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, No. 76 Linjiang Road, Chongqing, 400010, China.

Global heart
|December 9, 2024
PubMed
概括

糖尿病和外周动脉疾病 (DM-PAD) 具有共同的重大风险. 这项研究确定了DENND5B,C4A和CYP21A2作为关键基因,其中DENND5B显示出与DM-PAD病变发生有很强的因果关系.

关键词:
糖尿病综合外围动脉疾病 糖尿病综合外围动脉疾病多变量门德尔随机化基于总结数据的门德尔随机化.

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