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益生菌在 Vulvovaginal Candidiasis 中的作用:印度的一项随机对照的非盲目的试验

Apaopa Jemima Thekho¹, Vibhu Mendiratta¹, Taru Garg¹

¹From the Department of Dermatology and STD, Lady Hardinge Medical College and Sucheta Kriplani Hospital, New Delhi, India.

Indian journal of dermatology

|December 9, 2024

概括

将口服益生菌添加到 vulvovaginal candidiasis (VVC) 的抗真菌治疗中,改善了治愈率并降低了复发风险. 这种组合疗法为有效管理VVC提供了一个有希望的方法.

科学领域:

医学真菌学医学真菌学
微生物组研究微生物组研究
药理学药理学是指药理学的学科.

背景情况:

Vulvovaginal candidiasis (VVC) 是一种常见的真菌感染,通常用抗真菌药物治疗,但复发会影响一些患者.
以前的研究表明,益生菌可以缓解VVC症状,并防止复发,当与抗真菌治疗一起使用时.

研究的目的:

评估将口服益生菌与VVC标准抗真菌治疗相结合的疗效.
在一项随机对照试验中,将这种联合治疗与单独的抗真菌治疗进行比较.

主要方法:

60名新诊断的VVC患者被随机分为两组.
组A接受了口服可纳;组B接受了口服可纳加上2个月的口服益生菌 (Lactobacillus物种).
评估了临床,真菌学结果,复发率和副作用.

主要成果:

两组之间没有观察到临床或真菌学治愈率和复发率的统计学上显著差异 (P <0.05).
然而,B组 (益生菌+可纳) 的完全缓解率 (97%) 与A组 (单独可纳) 的完全缓解率 (90%) 相比较高.
在这两组治疗中都没有报告任何不良副作用.

结论:

将口服益生菌添加到常规抗真菌治疗VVC的治疗中,表明改善了临床和真菌学治愈率.
与益生菌结合治疗可能会导致VVC复发的可能性较低,相比单独的抗真菌治疗.
这种方法似乎是安全的,并且在管理VVC方面可能更有效.

关键词:

抗真菌药物是一种抗真菌药物.益生菌是一种益生菌.性健康性健康性健康性健康性健康性 vulvovaginal 候选性阴道炎的发生

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