结肠直肠形多体的内镜下粘膜剖析
Johanna Katharina Jakobs1, Malte Zumblick1, Susanne von Gerlach2
1Gastroenterology, University Hospital of Giessen and Marburg Campus Marburg, Marburg, Germany.
Endoscopy international open
|December 9, 2024
概括
内镜下粘膜切割 (ESD) 能够有效切除具有宽茎的大型脚结肠聚体,从而达到高的阻断和治愈切除率. 这种技术确保了精确的组织学分期,以改善患者的风险分类和治疗.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 在瘤学瘤学.
背景情况:
- 准确的组织学分期的形结肠多体需要块切除,包括茎.
- 对于大型的息肉或具有宽茎的息肉来说,传统的陷切除可能具有挑战性.
- 在这些具有挑战性的病例中,内镜下粘膜剖析 (ESD) 的可行性正在被探索.
研究的目的:
- 评估内镜下粘膜切割 (ESD) 的可行性和有效性,以切除具有宽茎的大型形结肠多.
- 通过使用ESD来评估块切除率,R0切除率和治愈切除率.
- 根据ESD确定组织学分期和风险分类的准确性.
主要方法:
- 一项前性研究包括在2019年2月至2021年11月期间患有大型脚型息肉 (直径≥20毫米或茎>5毫米) 的患者.
- 使用ESD技术切除了所有多,包括在下内注射后在其底部剖析多茎.
- 收集的数据包括多的特征,切除结果,组织学发现和不良事件.
主要成果:
- 25名患者接受了ESD用于大脚的息肉,实现了100%的块切除.
- 中位数的多体大小为30×25×17毫米,其中大多数位于西格结肠.
- 组织学检查显示32%的病例有腺瘤,高度内皮质瘤和腺癌. R0切除率为100%,治愈切除率为96%没有严重的不良事件.
结论:
- 内镜下粘膜切割 (ESD) 是一种可行且有效的方法,可以在大型脚结肠多中实现高阻断率和R0切割率.
- 高治愈切除率 (96%) 强调了ESD在准确的风险分类中的作用,特别是考虑到很大一部分 (32%) 的息肉含有腺癌.
- ESD提供了一种安全有效的替代传统方法,用于管理复杂的形息肉,提高诊断准确性和患者的结果.
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