从2022年到2023年改善腹膜透析液培养-阳性性产量
Jenna A van der Vyver1, Teena Thomas1,2
1Department of Clinical Microbiology and Infectious Diseases, Faculty of Health Science, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
Southern African journal of infectious diseases
|December 9, 2024
概括
在腹膜透析袋中引入血培养瓶使腹膜炎的培养阳性增加了一倍. 然而,培养负结果仍然很高,表明需要进一步改进微生物学测试的方法.
科学领域:
- 临床微生物学 临床微生物学
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 通过对腹腔透析 (PD) 袋进行微生物学测试来诊断腹腔炎,经常会产生培养负样本,超过国际腹腔透析协会推的15%的门.
研究的目的:
- 评估实施血液培养 (B / C) 瓶化步骤对PD袋测试中培养阳性产量和培养负率的影响.
- 确定修订后的方法是否减少了培养负结果的发生率,这是围炎管理的关键因素.
主要方法:
- 对来自国家卫生实验室服务 (NHLS) 中央数据仓库 (CDW) 的数据进行了追溯分析.
- 培养阳性和培养阴性结果在两个时期之间进行了比较:2022年6月至12月 (非B / C瓶子方法) 和2023年1月至7月 (B / C瓶子方法).
主要成果:
- 与非B/C瓶方法相比,B/C瓶方法的实施显著提高了培养阳性产量,从23%提高到51%.
- 尽管阳性率有所提高,但B/C瓶式方法的培养负性产量仍然高,为49%.
结论:
- 添加B/C瓶化步骤使PD袋的微生物学测试的培养阳性产量增加了一倍以上.
- 培养负结果的持续高百分比需要对实验室方法进行进一步的修改,以优化腹膜炎诊断和患者管理.
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