数字心电图复合物用于 Paroxysmal 心房的风险分层
A V Frolov1, O P Melnikova2, A P Vorobiev2
1DSc, Professor, Head of the Laboratory of Medical Information Technologies; Republican Scientific and Practical Centre "Cardiology", Ministry of Health of the Republic of Belarus, 110 R. Luxembourg St., Minsk, 220036, Belarus.
Sovremennye tekhnologii v meditsine
|December 9, 2024
概括
一个新的系统,Intecard 8.1,使用心电图在鼻腔节律中识别隐藏的心房动 (AF). 它分析了P波标记物,在预测心脏病患者的AF发作方面显示出高准确度.
科学领域:
- 心脏病学和医疗信息学
- 电心电图和心律失常检测
- 生物医学工程和信号处理.
背景情况:
- 隐藏的心房动 (AF) 带来了诊断挑战,通常需要先进的检测方法.
- 鼻腔节律中的标准心电图可能不会显示间歇性AF,因此需要分析微妙的电动不稳定性标志物.
- 早期识别患有隐性AF风险的个体对于及时干预和预防中风至关重要.
研究的目的:
- 开发和临床验证一个硬件软件系统,用于识别隐藏AF的预测因子,使用脉节律中的12导心电图.
- 评估特定的P波特征和衍生得出的分数作为心房电动不稳定性的指标.
- 评估该系统在预测患有缺血性心脏病或扩张性心肌病的患者的AF发作中的有效性.
主要方法:
- 开发"Intecard 8.1"系统,分析 3-5 分钟内心电图记录的鼻腔节律.
- 标记物的评估:P波幅度 (<0.1 mV),持续时间 (>120 ms),心房间隔,终端P波面积 (<-4 mV·ms) 和MVP得分 (>3).
- 120名患者的临床试验;用于改进P波检测的相变换方法.
主要成果:
- 在Intecard 8.1系统中,发现了18.3%的患者在12-22个月内出现了随后的AF发作.
- 患有AF的患者显示P波幅降低 (p=0.029),持续时间增加 (p<0.001),MVP得分更高 (p<0.01).
- 最值得关注的评分 (>3) 显示出高预后意义 (AUC=0.988),92%的灵敏度和89%的特异性预测隐藏的AF.
结论:
- 数字电心电图复合体"Intecard 8.1"有效地识别高风险的患者隐藏的AF使用标准ECGs在鼻腔节律.
- 对P波参数的动态评估可以进行个性化的风险分层和心房的管理.
- 该系统为心脏病学中早期检测和预防策略提供了宝贵的工具.
更多相关视频
08:10Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
Published on: July 20, 2022
1.6K
08:05Optimization of Transesophageal Atrial Pacing to Assess Atrial Fibrillation Susceptibility in Mice
Published on: June 29, 2022
2.6K
相关概念视频
01:29Electrocardiogram
2.2K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
2.2K
01:28Electrocardiogram Fundamentals
515
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
515
01:24ECG Interpretation of Rhythms
498
An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage....
498
01:28Disturbances in Heart Rhythm
904
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
904
01:25Correlation between ECG and Cardiac Cycle
3.4K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
3.4K
01:30Cardiac Action Potential
973
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
973