确定糖尿病脏病患者的营养状况和蛋白质能量浪费
Elif Karakas1, Hatice Colak2, Fatma Esra Gunes3
1Department of Nutrition and Dietetics, Marmara University Institute of Health Sciences, Istanbul, Turkiye.
Northern clinics of Istanbul
|December 9, 2024
概括
蛋白质能量浪费 (PEW) 在3期和4期糖尿病病 (DN) 患者中很普遍. 随着糖尿病脏病发病的晚期,PEW的患病率增加,PEW是一种比主观全球评估 (SGA) 更有效的营养不良评估.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 糖尿病病 (DN) 是糖尿病的常见并发症,导致损伤.
- 蛋白质能量浪费 (PEW) 是慢性病 (CKD) 患者的一个重大问题.
- 了解非透析DN患者的营养状况对于预后至关重要.
研究的目的:
- 评估患有3期和4期糖尿病病 (DN-3和DN-4) 的患者的营养状况.
- 确定DN阶段对蛋白质能量浪费 (PEW) 预后的影响.
主要方法:
- 收集了49名非透析DN患者 (DN-3和DN-4) 的人口统计,人体测量,生物化学,食物摄入量和主观全球评估 (SGA) 的数据.
- 使用国际脏营养和新陈代谢学会 (ISRNM) 的标准来诊断PEW.
主要成果:
- 在DN的后期阶段观察到PEW的更高患病率.
- 与DN-4患者相比,与DN-3患者相比,DN-4患者的体重,肌肉质量,肌素,微专尿和eGFR显著不同.
- 尽管建议充足的能量和宏观营养素摄入量,但26.5%的患者表现出PEW.
结论:
- 在土耳其的非透析DN患者中存在PEW,其患病率随疾病阶段的增加而增加.
- 营养素摄入量总体上是充足的,但PEW仍然发生,表明其他有助于因素.
- 使用ISRNM标准的PEW评估比SGA更有效地识别这些患者的营养不良.
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