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Updated: Jun 5, 2025

Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches
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Analysis of Somatic Hypermutation in the JH4 intron of Germinal Center B cells from Mouse Peyer's Patches

Published on: April 20, 2021

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节省的B细胞受体体体质突变的广泛背景模型

Kevin Sung, Mackenzie M Johnson, Will Dumm

    bioRxiv : the preprint server for biology
    |December 9, 2024
    PubMed
    概括

    这项研究使用高效的"节约性"方法模拟体质突变 (SHM). 这些模型以更少的参数捕获更广泛的核酸语境,改进了对抗体多样性和进化的分析.

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