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Updated: Jun 5, 2025

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在SARS-CoV-2 nsp1中自然发生的N端突变会影响先天免疫调节,但不会影响病毒的毒性

Ruchi Rani, Mohammed Nooruzzaman, Leonardo C Caserta

    bioRxiv : the preprint server for biology
    |December 9, 2024
    PubMed
    概括

    确定了两种SARS-CoV-2 nsp1删除变体 (Δ82-85和Δ83-86),显示出抑制免疫通路的能力降低. 这些nsp1突变并没有影响子的病毒传播,毒性或病原性.

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