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Updated: Jun 5, 2025

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
07:51

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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GABRA1框架转移变体会损害GABAA受体蛋白质稳定

Marnie P Williams1, Ya-Juan Wang1, Jing-Qiong Kang2

  • 1Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.

bioRxiv : the preprint server for biology
|December 9, 2024
PubMed
概括

在GABRA1基因中的四种位变异损害了胺黄油酸甲型受体 (GABAAR) 功能. 这些变异导致蛋白质错误折叠和细胞表面表达减少,导致遗传性病原体.

关键词:
在F272fs287X中使用.在GABAA受体中,GABAA受体是K401fs425XX 的时间在S326fs328X中,您可以使用S326fs328X.在V290fs299X中,V290fs299X是V290fs299X中的一个.降解降解降解降解降解.细胞内膜网膜的内oplasmic网膜.是一种.折叠 折叠 折叠 折叠框架转移变体的变体蛋白质稳定性 蛋白质稳定性走私和贩运的人口贩运

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