对抗精神病药物和长期运作的文献进行理解:认真对待自然历史和个性化
1Department of Psychiatry, Case Western Reserve University, Cleveland, OH, USA.
Psychological medicine
|December 9, 2024
概括
长期使用抗精神病药物需要个性化护理. 虽然有效的症状管理,仔细解释长期影响的功能对于治疗决策至关重要.
科学领域:
- 精神病学是一个精神病学.
- 临床药理学 临床药理学
背景情况:
- 长期使用抗精神病药物在治疗精神疾病方面很常见.
- 人们担心这些药物对个人功能随着时间的推移的影响.
研究的目的:
- 批判性地评估长期使用抗精神病药物与个人功能之间的关系.
- 强调临床影响和个性化患者护理的需要.
主要方法:
- 关键研究的综述,包括OPUS研究,芝加哥后续研究,Mesifos试验和RADAR试验.
- 对抗精神病药物的有效性和长期结果现有研究的分析.
主要成果:
- 抗精神病药物在症状管理中显示短期有效性.
- 对功能的长期影响是复杂的,需要仔细解释,受疾病轨迹和患者特征的影响.
结论:
- 目前的研究并不支持对大多数患者的常规抗精神病药物停用或剂量减少.
- 证据强调了个性化治疗的必要性,并支持对大量患者的剂量减少或停止治疗,在这种情况下,益处超过风险.
关键词:
美国的GAF是GAF,GAF是GAF.停止使用 停止使用剂量降低剂量降低的方法一个正常的运作.由于它具有阳性性,所以它具有阳性性.自然历史,自然历史.观察性研究是指观察性研究.个性化个性化个性化心理药理学 心理药理学精神错乱是一种精神病.精神分裂症患者 精神分裂症患者更多相关视频
12:00Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
Published on: November 19, 2014
12.9K
05:52Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
14.9K
相关概念视频
Psychosis: Goals of Pharmacotherapy
103
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
103
Drug Therapy
39
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
39
Psychosis and Antipsychotic Drugs: Overview
176
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
176
Psychological and Sociocultural Causes of Schizophrenia
71
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
71
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
453
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
453
Longitudinal Research
11.8K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.8K
