Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Long-term Depression01:03

Long-term Depression

2.5K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
2.5K
Muscle Stimulation Frequency01:22

Muscle Stimulation Frequency

2.0K
The contraction strength of muscles is regulated by motor neurons, which modulate the frequency of action potentials dispatched to the motor units based on the body's requirements. This process of varying the muscle stimulation frequency allows muscles to contract with a force that is precisely tailored to the needs of the moment, whether lifting a feather or a heavy box.
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
2.0K
Long-term Potentiation01:35

Long-term Potentiation

54.8K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
54.8K
Relaxation of Skeletal Muscles01:29

Relaxation of Skeletal Muscles

3.0K
The period of muscle contraction primarily influences the duration of stimulation at the neuromuscular junction (NMJ), the presence of free calcium ions in the sarcoplasm, and the availability of energy or ATP to support contractions.
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
3.0K
Motor Unit Stimulation01:20

Motor Unit Stimulation

1.4K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
1.4K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Moderate altitude-mimicking CO-induced inhibition of hemoglobin oxygen binding decreased middle-distance swimming speed in male national-level swimmers.

European journal of applied physiology·2026
Same author

Combined torso and foot heat exposure reduces acute <i>ad libitum</i> energy intake in young adults.

Temperature (Austin, Tex.)·2026
Same author

Excess of post-resistance exercise energy expenditure: a comparison between morning and evening.

European journal of applied physiology·2026
Same author

The 4th P: Helping Nursing Students Pitch Evidence-Informed Projects.

Nurse educator·2026
Same author

Metabolic Health and Fitness Do Not Differ Substantially Between Overweight Adults With and Without α-Actinin-3 Deficiency.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Association between body mass index and frailty for middle-aged and older adults in Japan: a cross-sectional study of the Osaka health disparity solution program.

BMC public health·2026
Same journal

Augmenting β2-adrenergic signaling during exercise to enhance anti-tumor immune function.

Exercise and sport sciences reviews·2026
Same journal

Exercise and Sport Sciences Reviews: 2025 Paper of the Year.

Exercise and sport sciences reviews·2026
Same journal

Limb Disuse Trials in Humans: Key Insights on Study Design, Ethics, and Project Execution.

Exercise and sport sciences reviews·2026
Same journal

Integrating Astronomical Seasonal Phase into Physical Activity Research.

Exercise and sport sciences reviews·2026
Same journal

microRNA-1: A Master Regulator of Metabolism Governing Skeletal Muscle Hypertrophy.

Exercise and sport sciences reviews·2026
Same journal

Acute Exercise and Cognitive Improvement: A Neuromodulatory Perspective.

Exercise and sport sciences reviews·2026
查看所有相关文章

相关实验视频

Updated: Jun 5, 2025

Assessment of Long-term Depression Induction in Adult Cerebellar Slices
09:30

Assessment of Long-term Depression Induction in Adult Cerebellar Slices

Published on: October 16, 2019

6.9K

背后的任务依赖机制 长期的低频力压力

Andrew J Richards1, Daiki Watanabe2, Takashi Yamada3

  • 1Muscle Health Research Centre, School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada.

Exercise and sport sciences reviews
|December 9, 2024
PubMed
概括
此摘要是机器生成的。

长时间的低频力压力 (PLFFD) 损害了运动后肌肉力量的恢复. 本研究调查了任务需求如何影响PLFFD中的激发-收缩合,并审查了缓解策略.

更多相关视频

Physiological Recordings of High and Low Output NMJs on the Crayfish Leg Extensor Muscle
10:00

Physiological Recordings of High and Low Output NMJs on the Crayfish Leg Extensor Muscle

Published on: November 17, 2010

11.7K
Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
09:51

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System

Published on: January 1, 2018

11.5K

相关实验视频

Last Updated: Jun 5, 2025

Assessment of Long-term Depression Induction in Adult Cerebellar Slices
09:30

Assessment of Long-term Depression Induction in Adult Cerebellar Slices

Published on: October 16, 2019

6.9K
Physiological Recordings of High and Low Output NMJs on the Crayfish Leg Extensor Muscle
10:00

Physiological Recordings of High and Low Output NMJs on the Crayfish Leg Extensor Muscle

Published on: November 17, 2010

11.7K
Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System
09:51

Recording Synaptic Plasticity in Acute Hippocampal Slices Maintained in a Small-volume Recycling-, Perfusion-, and Submersion-type Chamber System

Published on: January 1, 2018

11.5K

科学领域:

  • 运动生理学 运动生理学
  • 肌肉生理学 肌肉生理学
  • 神经肌肉功能 神经肌肉功能

背景情况:

  • 长时间的低频力压力 (PLFFD) 描述了运动后亚最大肌肉力量的缓慢恢复.
  • 肌肉内机制,特别是受损的激发 - 收缩 (EC) 合,都与PLFFD有关.
  • 了解特定任务的EC合赤字对于有针对性的干预至关重要.

研究的目的:

  • 为了研究长期低频力压力中受损的激发 - 收缩合的任务依赖性.
  • 为了比较EC合缺陷在代谢和机械要求较高的运动之间的贡献.
  • 审查旨在减轻PLFFD的干预措施.

主要方法:

  • 基于运动类型 (代谢与机械) 的EC合损伤的假设差异.
  • 对PLFFD,EC合和运动生理学现有文献的审查.
  • 对减缓力回收的因素进行分析.

主要成果:

  • 假设激发-收缩合的损伤是PLFFD的一个重要因素.
  • 预计EC合缺陷对PLFFD的贡献在代谢和机械要求较高的任务之间有所不同.
  • 讨论了各种干预措施缓解PLFFD的证据.

结论:

  • 激发-收缩合的特定任务缺陷可能会以不同的方式导致长期的低频力压力.
  • 需要进一步的研究来阐明精确的机制,并优化肌肉力量恢复的干预措施.