阻塞性睡眠呼吸暂停的最大部进度的种族差异:系统性审查和元分析
Douglas P Nanu1,2, Tanner J Diemer1,3, Shaun A Nguyen1
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA.
Sleep & breathing = Schlaf & Atmung
|December 9, 2024
概括
这一元分析揭示了因阻塞性睡眠呼吸暂停 (OSA) 的上部推进手术 (MMA) 后的结果在各族群中存在显著差异. 与白人和拉丁裔相比,亚洲人在睡眠呼吸暂停指标上有更大的改善.
科学领域:
- 睡眠医学 睡眠医学
- 手术结果研究研究.
- 阻塞性睡眠呼吸暂停 (OSA) 是一种
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍影响睡眠质量和心血管健康的疾病.
- 大口前进 (MMA) 是一种通过增加上呼吸道大小来治疗OSA的手术干预.
- 越来越多地认识到OSA患病率和治疗反应的种族和种族差异.
研究的目的:
- 调查不同种族/种族群体中OSAMMA手术后的多睡眠,脑力测量和主观结果的差异.
- 为了比较MMA在治疗OSA中的有效性,在高加索,亚洲和拉丁裔患者群体中.
主要方法:
- 根据PRISMA指南进行了全面的元分析.
- 文献搜索包括COCHRANE图书馆,CINAHL,PubMed和Scopus数据库,截至2023年8月.
- 研究结果根据患者人数进行加权,使用千平方和I平方统计数据评估异质性.
主要成果:
- 该分析包括了20项研究,涉及469名患者 (257名白人,204名亚洲人,8名拉丁裔).
- 与白人和拉丁裔相比,亚洲人对呼吸暂停-呼吸暂停指数 (AHI) 的减少更大.
- 在睡眠呼吸暂停测试 (LSAT) 和爱普沃思睡眠度量 (ESS) 的可能性中,亚洲人的术后改善明显好于白人.
结论:
- 在MMA对OSA的结果中存在显著的种族/种族差异.
- 与白人相比,亚洲人经常在手术前呈现更严重的OSA,在AHI,LSAT和ESS中表现出优异的术后改善.
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