年轻人中与压力相关的疾病 经过手术切除桃体或腺体的年轻人
Xue Xiao1,2, Fen Yang3, Li Yin4
1Department of Otolaryngology-Head and Neck Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
JAMA network open
|December 9, 2024
概括
童年时的桃切除术和腺切除术与增加患有压力相关疾病的风险有关,包括PTSD. 这种关联凸显了探索潜在健康状况及其对精神病治疗结果的影响的必要性.
科学领域:
- 精神病学是一个精神病学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 以前的研究表明,桃体切除术可能会增加精神疾病的风险.
- 桃体切除术/桃体切除术与与压力有关的疾病之间的关联仍然不清楚.
研究的目的:
- 调查手术切除桃体或腺体与随后的与压力有关的疾病风险之间的关联.
主要方法:
- 瑞典全国范围的注册数据从1981年至2016年.
- 队列研究比较暴露 (桃体切除/腺切除) 和未暴露的个体 (人口匹配和兄弟匹配).
- 考克斯的比例危险回归分析调整了混因子.
主要成果:
- 经过桃体切除/腺切除的个体,患有与压力相关的疾病 (HR, 1.43) 和PTSD (HR, 1.55) 的风险更高.
- 在兄弟匹配分析中,结果一致 (HR,1.34用于任何与压力相关的疾病;HR,1.41用于PTSD).
- 无论性别,年龄,手术后的时间或父母因素,都观察到风险增加,特别是在由于腺瘤疾病或睡眠/呼吸系统问题而进行的手术中.
结论:
- 早期的桃体切除术或桃体切除术与未来患有与压力相关疾病的风险增加有关.
- 需要进一步的研究,以了解腺桃体疾病和相关疾病在精神疾病发展中的作用.
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