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功能获取 NOTCH3 变种 由于衰老路径的激活,导致家族局部脂质变异

Abhimanyu Garg1, Chao Xing2,3,4, Anil K Agarwal1

  • 1Section of Nutrition and Metabolic Diseases, Division of Endocrinology, Department of Internal Medicine, Center for Human Nutrition, UT Southwestern Medical Center, Dallas, TX.

Diabetes
|December 9, 2024
PubMed
概括

新的NOTCH3基因变异导致一种新的家族性局部脂质变异 (FPL) 形式. 这一发现通过激活衰老途径,将NOTCH3突变与FPL联系起来,为诊断早期糖尿病患者提供了洞察力.

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