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Updated: Jun 5, 2025

Monitoring eIF4F Assembly by Measuring eIF4E-eIF4G Interaction in Live Cells
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Published on: May 1, 2020

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在T细胞淋巴瘤中,由eIF4E和XPO1调节GATA-3依赖的转录组和瘤微环境

Nermin Kady1,2, Suhaib Abdelrahman1, Ahmar M Rauf1

  • 1Division of Hematology and Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI.

Blood
|December 9, 2024
PubMed
概括

核出口蛋白XPO1在T细胞淋巴瘤 (TCL) 和它们的微观环境中高度表达. 用selinexor准XPO1显示出治疗这些具有挑战性的癌症的前景.

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