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主体限制因子SERINC5通过负调节NF-κB信号传递来抑制HIV-1转录

Weiting Li1, Meng Qu2, Tianxin Zhang2

  • 1State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases/Key Laboratory for Zoonosis Research of the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, China.

The Journal of biological chemistry
|December 9, 2024
PubMed
概括

血清结合剂5 (SER5) 通过向NF-κB信号来抑制HIV-1的转录. 它降解关键蛋白MDA5和RIG-I,阻断病毒基因表达并限制HIV-1复制.

关键词:
艾滋病病毒-1 艾滋病病毒-1MDA5 MDA5 MDA5 的意思是什么意思通过NF-κB信号通路传递信号.在RIG-I中,RIG-I是指RIG-I.在SERINC5中使用.转录 转录 是一种转录.

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