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跨性别男性的生殖功能和生育能力的保护:一系列法国案例
Charlotte Dupont1, Sophie Grateau2, Emilie Moreau2
1Service de Biologie de la Reproduction CECOS, Hôpital Tenon (AP-HP), Sorbonne-Université 75020 PARIS, France; Sorbonne Université, Centre de recherche Saint-Antoine, Inserm US938 75012 PARIS, France.
Journal of gynecology obstetrics and human reproduction
|December 9, 2024
概括
通过卵细胞玻璃化保存生育能力是接受性别肯定激素治疗的跨性别男性的可行选择. 结果与 cisgender 女人相似,为未来的父母提供了希望.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 跨性别者健康 跨性别者健康
- 保护生育能力 保护生育能力
背景情况:
- 跨性别男性因性别肯定激素治疗 (GAHT) 和手术而面临独特的生殖挑战.
- 虽然GAHT诱导的缺血常常是可逆的,但长期的生育能力和后代健康影响尚不清楚.
- 父母是跨性别男性的一个重要考虑因素,需要生育保护 (FP) 选项.
研究的目的:
- 为了比较经过生育保护的跨性别男性的卵巢刺激结果与异性女性的卵巢刺激结果.
- 评估对跨性别男性的卵细胞玻璃化可行性和有效性.
主要方法:
- 这是一项回顾性研究,将13名接受卵巢刺激的跨性别男性与13名匹配的 cisgender 雌性卵细胞捐赠者进行了比较.
- 从2018年6月到2022年2月收集的数据.
主要成果:
- 在跨性别男性和 cisgender 女性之间没有观察到卵巢刺激结果的显著差异.
- 关键指标包括刺激持续时间,FSH剂量,取回的卵细胞和获得的成熟卵细胞.
结论:
- 卵巢刺激后的卵细胞玻璃化对于跨性别男性来说是可行的和有效的.
- 结果与 cisgender 女人相似,支持FP 作为一个成功的选择.
- 需要进行更大规模的研究来证实长期成功率.
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