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Updated: Jun 23, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

计算机对平行DNA的折叠G-四重复:搭便车者指南对形态空间的指南

Michal Janeček1, Petra Kührová2,3, Vojtěch Mlýnský2,3,4

  • 1Department of Physical Chemistry, Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic.

Journal of computational chemistry
|December 9, 2024
PubMed
概括

这项研究提出了一种新的计算方法来建模瓜四重复 (GQ) 折叠路径. 该协议有助于了解治疗应用的GQ稳定性和动态.

关键词:
这就是DNA四重复性.计算式折叠方式增强采样 提升采样动力分区机制的动力分区机制形态动力学是什么意思分子动力学分子动力学着弹性带的弹性带.路径CVCV 路径过渡路径采样 过渡路径采样

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