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TGFβ特异性T细胞的抗瘤活性取决于IL-6信号传递

Maria Perez-Penco1, Mikkel Byrdal1, Lucia Lara de la Torre1

  • 1National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital, Herlev, Denmark.

Cellular & molecular immunology
|December 9, 2024
PubMed
概括

干白素-6 (IL-6) 对于TGFβ特异性T细胞在胰腺癌 (PC) 免疫治疗中的有效性至关重要. 用抗体阻止IL-6受体 (IL-6R) 可以阻碍抗瘤免疫力并降低治疗效率.

关键词:
在IL-6的研究中,IL-6被认为是IL-6的基因.在TGFβ中,TGFβ是TGFβ.免疫抑制是一种免疫抑制.瘤微环境是一个微环境.疫苗,疫苗,疫苗的使用情况.

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