臭氧处理调节了新鲜切割的皮塔亚多提取物对抗运动疲劳的影响
Chen Li1, Zhaoxia Wu2, Xiaofei Yang3
1College of Food and Health, Jinzhou Medical University, Jinzhou, China.
Frontiers in nutrition
|December 10, 2024
概括
臭氧处理通过提高抗氧化能力和调节新陈代谢来增强皮塔亚多的抗疲劳作用. 这种方法提供了一种可行的方法来促进多营养和对抗运动疲劳.
科学领域:
- 植物生物化学 植物生物化学
- 运动生理学 运动生理学
- 营养科学 营养科学
背景情况:
- 植物多因其抗疲劳特性而闻名,受其含量和提取能力的影响.
- 以前的研究表明,臭氧处理会改变皮塔亚多的生物效应.
研究的目的:
- 调查臭氧处理对新鲜切割的皮塔亚多提取物的抗运动疲劳作用的监管机制.
- 评估臭氧处理的皮塔亚多对小鼠运动表现和生理标志物的影响.
主要方法:
- 使用C57BL/6J小鼠来评估臭氧处理的皮塔亚多提取物对抗运动疲劳的影响.
- 分析了运动疲劳时间,抗氧化能力,MDA含量,肝糖原和器官重量.
- 采用RT-PCR和网络药理学来探索分子调节机制.
主要成果:
- 与未经处理的对照组相比,经过臭氧处理的皮塔亚多 (OP) 显著增加了11.86%的耗尽时间.
- OP治疗将总抗氧化能力提高了54.17%,MDA含量降低了32.8%,肝糖原增加了85.71%.
- OP调节了基质代谢,保护了肌肉和内脏体重,激活了PI3K/AKT,并降低了SRC/STAT3,与网络药理学发现和增加肠道微生物群多样性相一致.
结论:
- 臭氧处理是一种可行的策略,可以增强皮塔亚多的抗疲劳功效.
- 增强的效果归因于改善的抗氧化剂状态,代谢调节和特定信号通路的调节.
- 臭氧处理是改善皮塔亚多的营养价值和生物活性的一种可行的方法.
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