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使用翻译科学效益模型检查 QUARTET USA 试验的影响

Guhan Iyer¹, Danielle Lazar², Abigail S Baldridge^3,4

¹Cardiovascular Division and Global Health Center, Washington University in St. Louis., St. Louis. MO, USA.

Journal of clinical and translational science

|December 10, 2024

概括

翻译科学效益模型 (TSBM) 评估了 QUARTET USA 试验,发现了显著的临床和社区影响. 该模型有助于评估翻译研究的价值,并可指导未来的心血管研究.

科学领域:

翻译科学翻译科学
心血管研究研究心血管研究
健康结果研究研究结果

背景情况:

评估翻译研究的全部价值需要评估超越学术指标的好处.
美国四重奏试验是一项重要的心血管研究.

研究的目的:

用翻译科学效益模型 (TSBM) 评估 QUARTET USA 试验的影响.
在临床,社区,经济和政策领域识别和量化各种好处.

主要方法:

应用TSBM框架,评估30个不同的好处.
在TSBM的四个领域内分析Quartet USA试验数据.

主要成果:

美国Quartet试验在临床和社区领域的六个领域产生了影响.
在社区和经济领域的两个额外领域中确定了潜在的影响.

结论:

TSBM 有效地支持翻译研究的价值评估,例如 QUARTET USA 试验.
该TSBM可以作为一个有价值的模板来评估未来的心血管研究计划.

关键词:

研究影响力研究影响力这种高血压,高血压.随机化试验是一种随机化试验.翻译科学是翻译科学.

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