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内皮细胞FUNDC1缺乏驱动肺高血压

Yandong Pei1, Dongfeng Ren1, Yuanhao Yin1

  • 1State Key Laboratory of Medicinal Chemistry Biology, Haihe Laboratory of Cell Ecosystem, College of Life Sciences (Y.P., D.R., Y.Y., J.S., Q.A., W.H., X. Luo, C.B., L. Zhu, Q.W., S.L., Y. Zhang, J.L., L.L., H.Z., Y.L., G.C., Q.C., X. Liao), Nankai University, China.

Circulation research
|December 10, 2024
PubMed
概括

通过损害内皮细胞功能,FUNDC1介导的线粒细胞衰减会导致肺高血压 (PH). 针对这种途径为PH提供了新的治疗策略.

关键词:
内皮细胞是内皮细胞.高血压,肺部高血压,肺部高血压.缺氧 缺氧是指缺氧的情况.类似胰岛素的.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.

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