瑞典青年患有多动症,自闭症和精神病并发症的执行功能行为表现:与社区对照的比较分析
Annelie Hamilton1, Pia Tallberg1,2, Frida Ilahi2
1Child and Adolescent, Psychiatric Clinic in Helsingborg, Helsingborg, Sweden.
概括
神经发育障碍 (NDD) 在青少年中显著影响行为执行功能 (EF),即使有并发症. 双NDD显示出比单个NDD更多的EF赤字,强调了NDD.
科学领域:
- 神经科学是一个神经科学.
- 儿童心理学 儿童心理学
- 精神病学是一个精神病学.
背景情况:
- 在患有神经发育障碍 (NDD) 的年轻人中,行为执行功能 (EF) 评估至关重要.
- 同病症和多个NDD对EF的影响需要进一步调查.
- 现有的评级尺度提供可靠的EF评估,但需要在复杂的临床样本中进行验证.
研究的目的:
- 为了比较年轻人与NDD的行为EF档案,与对照和非NDD精神病状况相比.
- 检查精神病并发症对NDD年轻人EF的影响.
- 为了区分单个和双重NDD诊断之间的EF缺陷.
主要方法:
- 使用了瑞典版本的执行职能行为评分清单 (BRIEF-2) 主要表格.
- 在不同组中比较EF档案:NDDs (有/没有并发症),非NDDs和对照.
- 包括79名患有精神疾病的青少年和151名匹配的对照.
主要成果:
- 与非NDD/对照组相比,患有NDD的青少年在所有领域都表现出显著的EF缺陷 (效果大小非常大).
- 仅NDD和NDD与并发症组之间没有发现显著的EF差异.
- 与单个NDD相比,双重NDD的年轻人在四个EF领域,特别是"转变"领域显示出更多的缺陷.
结论:
- 神经发育障碍是青少年临床显著行为EF缺陷的主要驱动因素,无论其他精神病诊断如何.
- 精神病并发症似乎不会加剧EF缺陷,除了NDD本身的影响.
- 双重NDD诊断带来了更大的执行功能挑战,特别是在认知灵活性 (Shift领域).
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