富血小板血及其衍生物的最新进展:用于组织工程和再生医学的治疗剂
Sayanti Shome1, M Kodieswaran1, Rajat Dadheech2
1Biomaterials and Tissue Engineering Laboratory, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India.
Progress in biomedical engineering (Bristol, England)
|December 10, 2024
概括
富血小板血 (PRP) 提供了显著的组织再生潜力. 本综述详细介绍PRP的制备,组织工程中的应用和临床发现,强调其在患者特异性疗法中的未来.
科学领域:
- 生物材料科学 生物材料科学
- 再生医学是一种再生医学.
- 细胞生物学 细胞生物学
背景情况:
- 富血小板血 (PRP) 是一种富含血小板,生长因子和生物活性分子的血度.
- 血小板在激活时释放必要的蛋白质,赋予PRP显著的组织再生特性.
- PRP可以作为富血小板血,血小板溶解物或纤维素矩阵用于治疗.
研究的目的:
- 审查各种PRP配方和制备技术.
- 探索PRP在组织工程中的当前和新兴应用.
- 讨论临床试验,发现和PRP在再生医学中的优化策略.
主要方法:
- 关于PRP制备,隔离和应用策略的文献综述.
- 分析PRP在各种组织工程结构 (如支架,水凝) 中的作用.
- 检查不同组织类型的临床试验数据和结果.
主要成果:
- 在肌肉骨,心血管,皮肤,肝脏和神经组织再生中,PRP具有广泛的适用性.
- 有各种实验室和商业方法用于PRP的制备和隔离.
- PRP被整合到先进的再生方法中,如3D生物打印和注射水凝.
结论:
- PRP是一种多功能治疗剂,在组织工程中具有巨大的潜力.
- 优化PRP的制备,输送和储存对于临床成功至关重要.
- 预计PRP将对未来的患者特异性再生医学应用作出重大贡献.
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