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Updated: Jun 5, 2025

A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants
06:35

A Scalable, Cell-Based Method for the Functional Assessment of Ube3a Variants

Published on: October 10, 2022

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在UBE2E2附近的非编码变异通过多基因效应器编排心脏代谢病变型

Yang Zhang1,2,3, Natalie L David2, Tristan Pesaresi2,3

  • 1School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, China.

JCI insight
|December 10, 2024
PubMed
概括

非编码DNA中的遗传变异可以通过影响多个基因来影响2型糖尿病等复杂疾病. 这项研究揭示了多基因调节效应,其中变异影响远处基因,有助于疾病机制.

关键词:
脂肪组织的脂肪组织.糖尿病 糖尿病 糖尿病内分泌学 在内分泌学.遗传变异是一种遗传变异.遗传学 遗传学 是一个

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